AstraZeneca secures tie-up with Chinese firm for weight loss drugs


AstraZeneca has unveiled a tie-up with Chinaโ€™s CSPC Pharmaceutical Group to ramp up development of experimental weight loss and diabetes drugs in a deal worth 18.5 billion US dollars (ยฃ13.4 billion) as it looks to tap further into the booming sector.

Under the deal, the FTSE 100 pharmaceutical giant will have access to the exclusive global rights, outside China, to CSPCโ€™s once-a-month dose technology portfolio for weight management to offer more convenient solutions to daily injections.

The companies will also collaborate on four further programmes, using CSPCโ€™s platforms for long-acting technology and AI-driven peptide drug discovery.

Sharon Barr, executive vice president and head of biopharmaceuticals research and development at AstraZeneca, said: โ€œThis strategic collaboration advances our weight management portfolio by delivering novel assets which complement our existing programmes.

โ€œIt will provide access to CSPCโ€™s proprietary, AI-enabled, peptide capabilities and platform technology, which have the potential to transform the treatment of obesity, helping to address adherence and convenience as key barriers to long-term therapeutic success.

โ€œThis is an important step in creating a portfolio of simple, scalable and sustainable options that can help people with obesity, and weight-related complications live better, healthier lives.โ€

Dongchen Cai, chairman of CSPC, added it was a โ€œwin-win collaborationโ€.

He said the deal will see the firms โ€œdeliver the next generation of treatments that build upon the emerging science, using our technology platforms and AstraZenecaโ€™s complementary capabilities and reach, to realise global health benefits for people in need of improved weight managementโ€.

It marks the latest agreement between the pair, which have already joined forces on projects, such as in artificial intelligence (AI).

For access to eight weight loss programmes in total, AstraZeneca will pay CSPC 1.2 billion dollars (ยฃ870 million) upfront, with up to a further 17.3 billion dollars (ยฃ12.6 billion) more if development and sales milestones are met.

The deal is expected to complete in the second quarter.

It sees AstraZeneca boost investment into the fast growing market for weight loss and diabetes drugs, which has until now been led by blockbuster brands Mounjaro, Ozempic and Wegovy.

It is estimated that almost three billion people worldwide are obese or overweight, according to AstraZeneca.

It said obesity is a โ€œchronic, relapsing, multifactorial disease and contributes to over 200 complicationsโ€.

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